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To overcome the short half-life and frequent subcutaneous administration of pramlintide, new amylin receptor agonists like cagrilintide have been developed

These results furthermore correlated with the reduction of CRP levels, which may suggest that anti-inflammatory action may be an important mechanism of the antidepressant effect of incretin-based drugs [121]

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Lancet 2: 20-21, 1964

Summary: The optimal timing for GLP-1 medications depends on the specific formulation: once-weekly preparations can be taken at any time of day, whilst oral semaglutide must be taken on an empty stomach in the morning